{
  "id": 442609,
  "title": "Stanford Ribonanza RNA Folding Discussion",
  "url": "/competitions/stanford-ribonanza-rna-folding/discussion/442609",
  "author_name": "Bhavesh Padharia",
  "post_date": "2023-09-23T12:32:33.408000",
  "votes": 0,
  "comment_count": 0,
  "views": 0,
  "content": "<p>It seems like you might be referring to \"RNAz,\" a program developed by researchers at Stanford University for predicting RNA secondary structures. RNA secondary structures are important because they can provide insights into the function and properties of RNA molecules.</p>\n<p>RNAz is a tool used for the detection of structurally conserved and thermodynamically stable RNA secondary structures in multiple sequence alignments. It evaluates the likelihood of a given sequence alignment forming a conserved RNA secondary structure by comparing it to a null model where the sequences are shuffled. If the predicted structure is more stable and conserved than expected by chance, it suggests the presence of a biologically functional RNA structure.</p>\n<p>The program uses a combination of thermodynamic and evolutionary models to make these predictions. RNAz can be useful for identifying functional non-coding RNAs, such as riboswitches, cis-regulatory elements, and other structured RNA elements, in a set of related sequences.</p>\n<p>**Share your Ideas **</p>",
  "messages": [
    {
      "id": 2452591,
      "postDate": "2023-09-23T12:32:33.410Z",
      "content": "<p>It seems like you might be referring to \"RNAz,\" a program developed by researchers at Stanford University for predicting RNA secondary structures. RNA secondary structures are important because they can provide insights into the function and properties of RNA molecules.</p>\n<p>RNAz is a tool used for the detection of structurally conserved and thermodynamically stable RNA secondary structures in multiple sequence alignments. It evaluates the likelihood of a given sequence alignment forming a conserved RNA secondary structure by comparing it to a null model where the sequences are shuffled. If the predicted structure is more stable and conserved than expected by chance, it suggests the presence of a biologically functional RNA structure.</p>\n<p>The program uses a combination of thermodynamic and evolutionary models to make these predictions. RNAz can be useful for identifying functional non-coding RNAs, such as riboswitches, cis-regulatory elements, and other structured RNA elements, in a set of related sequences.</p>\n<p>**Share your Ideas **</p>",
      "rawMarkdown": "It seems like you might be referring to \"RNAz,\" a program developed by researchers at Stanford University for predicting RNA secondary structures. RNA secondary structures are important because they can provide insights into the function and properties of RNA molecules.\n\nRNAz is a tool used for the detection of structurally conserved and thermodynamically stable RNA secondary structures in multiple sequence alignments. It evaluates the likelihood of a given sequence alignment forming a conserved RNA secondary structure by comparing it to a null model where the sequences are shuffled. If the predicted structure is more stable and conserved than expected by chance, it suggests the presence of a biologically functional RNA structure.\n\nThe program uses a combination of thermodynamic and evolutionary models to make these predictions. RNAz can be useful for identifying functional non-coding RNAs, such as riboswitches, cis-regulatory elements, and other structured RNA elements, in a set of related sequences.\n\n**Share your Ideas **\n\n"
    }
  ],
  "comments": [],
  "raw_markdown_by_id": {
    "2452591": "It seems like you might be referring to \"RNAz,\" a program developed by researchers at Stanford University for predicting RNA secondary structures. RNA secondary structures are important because they can provide insights into the function and properties of RNA molecules.\n\nRNAz is a tool used for the detection of structurally conserved and thermodynamically stable RNA secondary structures in multiple sequence alignments. It evaluates the likelihood of a given sequence alignment forming a conserved RNA secondary structure by comparing it to a null model where the sequences are shuffled. If the predicted structure is more stable and conserved than expected by chance, it suggests the presence of a biologically functional RNA structure.\n\nThe program uses a combination of thermodynamic and evolutionary models to make these predictions. RNAz can be useful for identifying functional non-coding RNAs, such as riboswitches, cis-regulatory elements, and other structured RNA elements, in a set of related sequences.\n\n**Share your Ideas **\n\n"
  }
}