{ "id": 171940, "title": "Lung function decline", "url": "/competitions/osic-pulmonary-fibrosis-progression/discussion/171940", "author_name": "Yasuoki Horiike", "post_date": "2020-08-03T03:40:40.657000", "votes": 3, "comment_count": 5, "views": 0, "content": "

Hi,

\n\n

Since lung function is affected not only by pulmonary lesions but also by the mass of the respiratory muscles, I would like to create a model that incorporates them as well to test it...

", "messages": [ { "id": 955880, "postDate": "2020-08-03T03:40:40.657Z", "content": "

Hi,

\n\n

Since lung function is affected not only by pulmonary lesions but also by the mass of the respiratory muscles, I would like to create a model that incorporates them as well to test it...

", "rawMarkdown": "Hi,\n\nSince lung function is affected not only by pulmonary lesions but also by the mass of the respiratory muscles, I would like to create a model that incorporates them as well to test it...", "votes": 3 }, { "id": 957510, "postDate": "2020-08-04T11:18:10.760Z", "content": "

Yes, I think so. Clinically, in certain types of interstitial pneumonia, slenderness and flattening of the thorax may be an indicator of disease progression. Therefore, I think the mass of the respiratory muscles and flattening of the thorax at a given point in time (although there is no clear criterion for flattening of the thorax) may affect respiratory function. Although we tend to focus only on lung lesions, respiratory function is affected by a variety of factors.

", "rawMarkdown": "Yes, I think so. Clinically, in certain types of interstitial pneumonia, slenderness and flattening of the thorax may be an indicator of disease progression. Therefore, I think the mass of the respiratory muscles and flattening of the thorax at a given point in time (although there is no clear criterion for flattening of the thorax) may affect respiratory function. Although we tend to focus only on lung lesions, respiratory function is affected by a variety of factors.", "replies": [ { "id": 966813, "postDate": "2020-08-11T17:15:15.703Z", "content": "

@yasuoki where is this info provided ? mass of respiratory muscles

", "rawMarkdown": "@yasuoki where is this info provided ? mass of respiratory muscles" }, { "id": 968464, "postDate": "2020-08-13T03:35:12.700Z", "rawMarkdown": "", "isDeleted": true }, { "id": 968466, "postDate": "2020-08-13T03:38:44.697Z", "content": "

Distinct profile and prognostic impact of body composition changes in idiopathic pulmonary fibrosis and idiopathic pleuroparenchymal fibroelastosis
\ndoi.org/10.1038/s41598-018-32478-z

\n

Frailty and geriatric conditions in older patients with idiopathic pulmonary fibrosis
\ndoi: 10.1016/j.rmed.2019.01.008

\n

etc.
\n

", "rawMarkdown": "Distinct profile and prognostic impact of body composition changes in idiopathic pulmonary fibrosis and idiopathic pleuroparenchymal fibroelastosis\ndoi.org/10.1038/s41598-018-32478-z\n\nFrailty and geriatric conditions in older patients with idiopathic pulmonary fibrosis\ndoi: 10.1016/j.rmed.2019.01.008\n\netc.\n[](url)" } ] }, { "id": 957216, "postDate": "2020-08-04T06:36:28.240Z", "content": "

Do you think muscle mass affects the progression as well?

", "rawMarkdown": "Do you think muscle mass affects the progression as well?" } ], "comments": [ { "id": 957510, "author_name": "Yasuoki Horiike", "author_url": "", "post_date": "2020-08-04T11:18:10.760000", "content": "

Yes, I think so. Clinically, in certain types of interstitial pneumonia, slenderness and flattening of the thorax may be an indicator of disease progression. Therefore, I think the mass of the respiratory muscles and flattening of the thorax at a given point in time (although there is no clear criterion for flattening of the thorax) may affect respiratory function. Although we tend to focus only on lung lesions, respiratory function is affected by a variety of factors.

", "votes": 0, "replies": [ { "id": 966813, "author_name": "Jaideep", "author_url": "", "post_date": "2020-08-11T17:15:15.703000", "content": "

@yasuoki where is this info provided ? mass of respiratory muscles

", "votes": 0, "replies": [] }, { "id": 968464, "author_name": "", "author_url": "", "post_date": "2020-08-13T03:35:12.700000", "content": "", "votes": 0, "replies": [] }, { "id": 968466, "author_name": "Yasuoki Horiike", "author_url": "", "post_date": "2020-08-13T03:38:44.697000", "content": "

Distinct profile and prognostic impact of body composition changes in idiopathic pulmonary fibrosis and idiopathic pleuroparenchymal fibroelastosis
\ndoi.org/10.1038/s41598-018-32478-z

\n

Frailty and geriatric conditions in older patients with idiopathic pulmonary fibrosis
\ndoi: 10.1016/j.rmed.2019.01.008

\n

etc.
\n

", "votes": 0, "replies": [] } ] }, { "id": 957216, "author_name": "Gunes Evitan", "author_url": "", "post_date": "2020-08-04T06:36:28.240000", "content": "

Do you think muscle mass affects the progression as well?

", "votes": 0, "replies": [] } ], "raw_markdown_by_id": { "955880": "Hi,\n\nSince lung function is affected not only by pulmonary lesions but also by the mass of the respiratory muscles, I would like to create a model that incorporates them as well to test it...", "957510": "Yes, I think so. Clinically, in certain types of interstitial pneumonia, slenderness and flattening of the thorax may be an indicator of disease progression. Therefore, I think the mass of the respiratory muscles and flattening of the thorax at a given point in time (although there is no clear criterion for flattening of the thorax) may affect respiratory function. Although we tend to focus only on lung lesions, respiratory function is affected by a variety of factors.", "957216": "Do you think muscle mass affects the progression as well?" } }