{ "id": 197572, "title": "Rapid Communication -What is kidney? The role and the type of glomerular disease-", "url": "/competitions/hubmap-kidney-segmentation/discussion/197572", "author_name": "", "post_date": "2020-11-17T04:09:40.653768400Z", "votes": 10, "comment_count": 4, "views": 0, "content": "

Rapid Communication

\n

Dear all,

\n

・Firstly, the kidney is the organs that \"excrete waste\".
\nI thought this site would be easier to understand for the general public, so I'm posting a link to it.

\n

https://www.niddk.nih.gov/health-information/kidney-disease/kidneys-how-they-work#:~:text=The%20kidneys%20are%20two%20bean,extra%20water%20to%20make%20urine.
\nhttps://www.youtube.com/watch?v=2eiLaFlTfKc

\n

・The kidney tissue is composed of three elements: (1) glomeruli, (2) tubules and (3) stroma / blood vessels.

\n

・The glomerulus is composed of endothelial cells, mesangial cells and substrate, basement membrane, and epithelial cells (octopus foot cells).
\nPlease refer to the following link for normal images.

\n

This PAS staining is the most common staining method to observe renal pathology. - it is generally common to look at the glomerulus at 100-400x.

\n

Reference:
\nhttps://www.kaggle.com/ihelon/hubmap-eda
\nhttps://www.kaggle.com/nayuts/hubmap-first-visualization

\n

The sample image provided in the notebook is at very low magnification.　
\n(I haven't seen the other images here yet, so it's hard to tell the overview.)

\n

Also in the Overview.

\n

\"Teams are invited to develop segmentation algorithms that identify glomeruli in the PAS stained microscopy data.\"
\nThere is possibility that participants is required to predict optimal segmentation from low magnification.

\n

Additionally, some patients on dialysis are due to glomerular abnormalities.
\nGlomerular diseases are as diverse as acute glomerulonephritis, IgA nephropathy, lupus nephritis, non-IgA proliferative glomerulonephritis, cryoglobulinemia microglobulinemia microalteration nephropathy rapidly progressive glomerulonephritis focal glomerulosclerosis microscopic polyangiitis membranous nephropathy Wegener's granulomatosis membranous proliferative glomerulonephritis Goodpasture's syndrome diabetic nephropathy amyloid nephropathy nephropathy nephropathy nephropathy nephropathy.
\nIt remains to be seen if these abnormal glomerular lesions are included in the current dataset.

\n

Here are sample images of these abnormal glomerular diseases.
\nhttps://www.kidneypathology.com/English_version/Histologic_patterns.html

\n

*This article is written by a novice kaggler, physician, but not a pathologist or a physician specializing in renal disease and
\nI hope to learn more about imaging in your Notebook/Discussion!

\n

Best,

", "messages": [ { "id": "1081414", "postDate": "11/17/2020 04:09:40", "content": "

Rapid Communication

\n

Dear all,

\n

・Firstly, the kidney is the organs that \"excrete waste\".
\nI thought this site would be easier to understand for the general public, so I'm posting a link to it.

\n

https://www.niddk.nih.gov/health-information/kidney-disease/kidneys-how-they-work#:~:text=The%20kidneys%20are%20two%20bean,extra%20water%20to%20make%20urine.
\nhttps://www.youtube.com/watch?v=2eiLaFlTfKc

\n

・The kidney tissue is composed of three elements: (1) glomeruli, (2) tubules and (3) stroma / blood vessels.

\n

・The glomerulus is composed of endothelial cells, mesangial cells and substrate, basement membrane, and epithelial cells (octopus foot cells).
\nPlease refer to the following link for normal images.

\n

This PAS staining is the most common staining method to observe renal pathology. - it is generally common to look at the glomerulus at 100-400x.

\n

Reference:
\nhttps://www.kaggle.com/ihelon/hubmap-eda
\nhttps://www.kaggle.com/nayuts/hubmap-first-visualization

\n

The sample image provided in the notebook is at very low magnification.　
\n(I haven't seen the other images here yet, so it's hard to tell the overview.)

\n

Also in the Overview.

\n

\"Teams are invited to develop segmentation algorithms that identify glomeruli in the PAS stained microscopy data.\"
\nThere is possibility that participants is required to predict optimal segmentation from low magnification.

\n

Additionally, some patients on dialysis are due to glomerular abnormalities.
\nGlomerular diseases are as diverse as acute glomerulonephritis, IgA nephropathy, lupus nephritis, non-IgA proliferative glomerulonephritis, cryoglobulinemia microglobulinemia microalteration nephropathy rapidly progressive glomerulonephritis focal glomerulosclerosis microscopic polyangiitis membranous nephropathy Wegener's granulomatosis membranous proliferative glomerulonephritis Goodpasture's syndrome diabetic nephropathy amyloid nephropathy nephropathy nephropathy nephropathy nephropathy.
\nIt remains to be seen if these abnormal glomerular lesions are included in the current dataset.

\n

Here are sample images of these abnormal glomerular diseases.
\nhttps://www.kidneypathology.com/English_version/Histologic_patterns.html

\n

*This article is written by a novice kaggler, physician, but not a pathologist or a physician specializing in renal disease and
\nI hope to learn more about imaging in your Notebook/Discussion!

\n

Best,

", "rawMarkdown": "Rapid Communication\n\nDear all,\n\n・Firstly, the kidney is the organs that \"excrete waste\".\nI thought this site would be easier to understand for the general public, so I'm posting a link to it.\n\nhttps://www.niddk.nih.gov/health-information/kidney-disease/kidneys-how-they-work#:~:text=The%20kidneys%20are%20two%20bean,extra%20water%20to%20make%20urine.\nhttps://www.youtube.com/watch?v=2eiLaFlTfKc\n\n・The kidney tissue is composed of three elements: (1) glomeruli, (2) tubules and (3) stroma / blood vessels.\n\n・The glomerulus is composed of endothelial cells, mesangial cells and substrate, basement membrane, and epithelial cells (octopus foot cells).\nPlease refer to the following link for normal images.\n\nThis PAS staining is the most common staining method to observe renal pathology. - it is generally common to look at the glomerulus at 100-400x.\n\nReference:\nhttps://www.kaggle.com/ihelon/hubmap-eda\nhttps://www.kaggle.com/nayuts/hubmap-first-visualization\n\nThe sample image provided in the notebook is at very low magnification.　\n(I haven't seen the other images here yet, so it's hard to tell the overview.)\n\nAlso in the Overview.\n\n\"Teams are invited to develop segmentation algorithms that identify glomeruli in the PAS stained microscopy data.\"\nThere is possibility that participants is required to predict optimal segmentation from low magnification.\n\nAdditionally, some patients on dialysis are due to glomerular abnormalities.\nGlomerular diseases are as diverse as acute glomerulonephritis, IgA nephropathy, lupus nephritis, non-IgA proliferative glomerulonephritis, cryoglobulinemia microglobulinemia microalteration nephropathy rapidly progressive glomerulonephritis focal glomerulosclerosis microscopic polyangiitis membranous nephropathy Wegener's granulomatosis membranous proliferative glomerulonephritis Goodpasture's syndrome diabetic nephropathy amyloid nephropathy nephropathy nephropathy nephropathy nephropathy.\nIt remains to be seen if these abnormal glomerular lesions are included in the current dataset.\n\n**Here are sample images of these abnormal glomerular diseases.**\nhttps://www.kidneypathology.com/English_version/Histologic_patterns.html\n\n*This article is written by a novice kaggler, physician, but not a pathologist or a physician specializing in renal disease and\nI hope to learn more about imaging in your Notebook/Discussion!\n\nBest,", "votes": null }, { "id": "1081665", "postDate": "11/17/2020 08:49:13", "content": "

@mourinho384
\nThank you for launching a nice discussion.
\nI would like to ask you a question.

\n

Do glomeruli include bodies of epithelial cells?
\nI checked the masks provided by the competition's hosts.
\nI do not have expertise in nephrology or pathology. Probably bodies of epithelial cells were not covered.
\nWhat is the border of glomerulus? Bowman's capsule?

", "rawMarkdown": "mourinho384 \nThank you for launching a nice discussion.\nI would like to ask you a question.\n\nDo glomeruli include bodies of epithelial cells?\nI checked the masks provided by the competition's hosts. \nI do not have expertise in nephrology or pathology. Probably bodies of epithelial cells were not covered.\nWhat is the border of glomerulus? Bowman's capsule?", "votes": null }, { "id": "1081979", "postDate": "11/17/2020 13:42:16", "content": "

Bowman's capsule is NOT part of the Glomerulus.

", "rawMarkdown": "Bowman's capsule is NOT part of the Glomerulus.", "votes": null }, { "id": "1082000", "postDate": "11/17/2020 14:02:15", "content": "

Thank you for your comments, @yosukeyama and @dlbsabu .
\nAgree with @dlbsabu 's opinion.

\n

First of all, the Bowman capsule is not part of the glomerulus. To compare it to an avocado skin (= Bowman's capsule) with a seed (= glomerulus) inside it.
\nSecondly, Talks about the epithelial cells. These are the ones around the glomerulus, but I think they are classified in this segmentation as well as the glomerulus.

", "rawMarkdown": "Thank you for your comments, @yosukeyama and @dlbsabu .\nAgree with @dlbsabu 's opinion.\n\nFirst of all, the Bowman capsule is not part of the glomerulus. To compare it to an avocado skin (= Bowman's capsule) with a seed (= glomerulus) inside it.\nSecondly, Talks about the epithelial cells. These are the ones around the glomerulus, but I think they are classified in this segmentation as well as the glomerulus.", "votes": null }, { "id": "1082084", "postDate": "11/17/2020 15:24:10", "content": "

Thank you for your replies, @dlbsabu and @mourinho384.

\n

I was confused because masks provided by the hosts covered a part of Bowman's capsule as a glomerulus.
\nThe example image is from this notebook https://www.kaggle.com/ihelon/hubmap-exploratory-data-analysis.

\n

Thanks to your explanation, I understood the definition of glomeruli.
\nThank you very much!

", "rawMarkdown": "Thank you for your replies, @dlbsabu and @mourinho384.\n\nI was confused because masks provided by the hosts covered a part of Bowman's capsule as a glomerulus.\nThe example image is from this notebook https://www.kaggle.com/ihelon/hubmap-exploratory-data-analysis.\n\nThanks to your explanation, I understood the definition of glomeruli.\nThank you very much!", "votes": null } ], "comments": [ { "id": 1081665, "author_name": "yosukeyama", "author_url": "", "post_date": "11/17/2020 08:49:13", "content": "

@mourinho384
\nThank you for launching a nice discussion.
\nI would like to ask you a question.

\n

Do glomeruli include bodies of epithelial cells?
\nI checked the masks provided by the competition's hosts.
\nI do not have expertise in nephrology or pathology. Probably bodies of epithelial cells were not covered.
\nWhat is the border of glomerulus? Bowman's capsule?

", "votes": null, "replies": [ { "id": 1081979, "author_name": "dlbsabu", "author_url": "", "post_date": "11/17/2020 13:42:16", "content": "

Bowman's capsule is NOT part of the Glomerulus.

", "votes": null, "replies": [] }, { "id": 1082000, "author_name": "mourinho384", "author_url": "", "post_date": "11/17/2020 14:02:15", "content": "

Thank you for your comments, @yosukeyama and @dlbsabu .
\nAgree with @dlbsabu 's opinion.

\n

First of all, the Bowman capsule is not part of the glomerulus. To compare it to an avocado skin (= Bowman's capsule) with a seed (= glomerulus) inside it.
\nSecondly, Talks about the epithelial cells. These are the ones around the glomerulus, but I think they are classified in this segmentation as well as the glomerulus.

", "votes": null, "replies": [] }, { "id": 1082084, "author_name": "yosukeyama", "author_url": "", "post_date": "11/17/2020 15:24:10", "content": "

Thank you for your replies, @dlbsabu and @mourinho384.

\n

I was confused because masks provided by the hosts covered a part of Bowman's capsule as a glomerulus.
\nThe example image is from this notebook https://www.kaggle.com/ihelon/hubmap-exploratory-data-analysis.

\n

Thanks to your explanation, I understood the definition of glomeruli.
\nThank you very much!

", "votes": null, "replies": [] } ] } ], "raw_markdown_by_id": { "1081414": "Rapid Communication\n\nDear all,\n\n・Firstly, the kidney is the organs that \"excrete waste\".\nI thought this site would be easier to understand for the general public, so I'm posting a link to it.\n\nhttps://www.niddk.nih.gov/health-information/kidney-disease/kidneys-how-they-work#:~:text=The%20kidneys%20are%20two%20bean,extra%20water%20to%20make%20urine.\nhttps://www.youtube.com/watch?v=2eiLaFlTfKc\n\n・The kidney tissue is composed of three elements: (1) glomeruli, (2) tubules and (3) stroma / blood vessels.\n\n・The glomerulus is composed of endothelial cells, mesangial cells and substrate, basement membrane, and epithelial cells (octopus foot cells).\nPlease refer to the following link for normal images.\n\nThis PAS staining is the most common staining method to observe renal pathology. - it is generally common to look at the glomerulus at 100-400x.\n\nReference:\nhttps://www.kaggle.com/ihelon/hubmap-eda\nhttps://www.kaggle.com/nayuts/hubmap-first-visualization\n\nThe sample image provided in the notebook is at very low magnification.　\n(I haven't seen the other images here yet, so it's hard to tell the overview.)\n\nAlso in the Overview.\n\n\"Teams are invited to develop segmentation algorithms that identify glomeruli in the PAS stained microscopy data.\"\nThere is possibility that participants is required to predict optimal segmentation from low magnification.\n\nAdditionally, some patients on dialysis are due to glomerular abnormalities.\nGlomerular diseases are as diverse as acute glomerulonephritis, IgA nephropathy, lupus nephritis, non-IgA proliferative glomerulonephritis, cryoglobulinemia microglobulinemia microalteration nephropathy rapidly progressive glomerulonephritis focal glomerulosclerosis microscopic polyangiitis membranous nephropathy Wegener's granulomatosis membranous proliferative glomerulonephritis Goodpasture's syndrome diabetic nephropathy amyloid nephropathy nephropathy nephropathy nephropathy nephropathy.\nIt remains to be seen if these abnormal glomerular lesions are included in the current dataset.\n\n**Here are sample images of these abnormal glomerular diseases.**\nhttps://www.kidneypathology.com/English_version/Histologic_patterns.html\n\n*This article is written by a novice kaggler, physician, but not a pathologist or a physician specializing in renal disease and\nI hope to learn more about imaging in your Notebook/Discussion!\n\nBest,", "1081665": "mourinho384 \nThank you for launching a nice discussion.\nI would like to ask you a question.\n\nDo glomeruli include bodies of epithelial cells?\nI checked the masks provided by the competition's hosts. \nI do not have expertise in nephrology or pathology. Probably bodies of epithelial cells were not covered.\nWhat is the border of glomerulus? Bowman's capsule?", "1081979": "Bowman's capsule is NOT part of the Glomerulus.", "1082000": "Thank you for your comments, @yosukeyama and @dlbsabu .\nAgree with @dlbsabu 's opinion.\n\nFirst of all, the Bowman capsule is not part of the glomerulus. To compare it to an avocado skin (= Bowman's capsule) with a seed (= glomerulus) inside it.\nSecondly, Talks about the epithelial cells. These are the ones around the glomerulus, but I think they are classified in this segmentation as well as the glomerulus.", "1082084": "Thank you for your replies, @dlbsabu and @mourinho384.\n\nI was confused because masks provided by the hosts covered a part of Bowman's capsule as a glomerulus.\nThe example image is from this notebook https://www.kaggle.com/ihelon/hubmap-exploratory-data-analysis.\n\nThanks to your explanation, I understood the definition of glomeruli.\nThank you very much!" }, "source": "meta" }