{
  "id": 103663,
  "title": "Difference between disease categories",
  "url": "/competitions/aptos2019-blindness-detection/discussion/103663",
  "author_name": "Caitlin",
  "post_date": "2019-08-10T18:18:43.279000",
  "votes": 5,
  "comment_count": 4,
  "views": 0,
  "content": "<p>Dear all,</p>\n\n<p>I was wondering, from a medical perspective, if someone is classified in category 3, they will still show the symptoms of category 1 and 2 on the retina image? Or do the early signs disappear/get replaced by the new symptoms that would put someone if disease category 3?</p>\n\n<p>Thank you!</p>",
  "messages": [
    {
      "id": 596500,
      "postDate": "2019-08-10T18:18:43.280Z",
      "content": "<p>Dear all,</p>\n\n<p>I was wondering, from a medical perspective, if someone is classified in category 3, they will still show the symptoms of category 1 and 2 on the retina image? Or do the early signs disappear/get replaced by the new symptoms that would put someone if disease category 3?</p>\n\n<p>Thank you!</p>",
      "rawMarkdown": "Dear all,\n\nI was wondering, from a medical perspective, if someone is classified in category 3, they will still show the symptoms of category 1 and 2 on the retina image? Or do the early signs disappear/get replaced by the new symptoms that would put someone if disease category 3?\n\nThank you!",
      "votes": 4
    },
    {
      "id": 598135,
      "postDate": "2019-08-13T07:25:39.667Z",
      "content": "<p>There are various grading protocols for diabetic retinopathy. For example: <a href=\"http://www.adcis.net/en/third-party/messidor/\">Messidor dataset</a> is graded using following:</p>\n\n<blockquote>\n  <p>0 -&gt; (Normal): (μA = 0) AND (H = 0)\n  1 -&gt; (0 &lt; μA &lt; = 5) AND (H = 0)<br>\n  2 -&gt; ((5 &lt; μA &lt; 15) OR (0 &lt; H &lt; 5)) AND (NV = 0)<br>\n  3 -&gt;(μA &gt;= 15) OR (H &gt;=5) OR (NV = 1)\n  where:\n      μA: number of microaneurysms\n      H: number of hemorrhages\n      NV = 1: neovascularization\n      NV = 0: no neovascularization</p>\n</blockquote>\n\n<p>There are others like Scottish grading protocol.\nDepending on above, category 2 will have symptoms of category 1. For example: If patient has 7 μA and 1 H (category 2), he still has minimum required for category 1.\nSo I guess early signs do not disappear, but is enhanced in a way.</p>\n\n<p><strong>Note:</strong> This is my own understanding. I'll really appreciate if someone with domain knowledge can shed more light.</p>",
      "rawMarkdown": "There are various grading protocols for diabetic retinopathy. For example: [Messidor dataset](http://www.adcis.net/en/third-party/messidor/) is graded using following:\n&gt; \n0 -&gt; (Normal): (μA = 0) AND (H = 0)\n1 -&gt; (0 &lt; μA &lt; = 5) AND (H = 0)<br>\n2 -&gt; ((5 &lt; μA &lt; 15) OR (0 &lt; H &lt; 5)) AND (NV = 0)<br>\n3 -&gt;(μA &gt;= 15) OR (H &gt;=5) OR (NV = 1)\nwhere:\n    μA: number of microaneurysms\n    H: number of hemorrhages\n    NV = 1: neovascularization\n    NV = 0: no neovascularization\n\nThere are others like Scottish grading protocol.\nDepending on above, category 2 will have symptoms of category 1. For example: If patient has 7 μA and 1 H (category 2), he still has minimum required for category 1.\nSo I guess early signs do not disappear, but is enhanced in a way.\n\n**Note:** This is my own understanding. I'll really appreciate if someone with domain knowledge can shed more light.",
      "votes": 2,
      "replies": [
        {
          "id": 598911,
          "postDate": "2019-08-14T08:04:01.130Z",
          "content": "<p>Do you know how current competition's dataset is graded? or how is its grading different than Messidor's?</p>",
          "rawMarkdown": "Do you know how current competition's dataset is graded? or how is its grading different than Messidor's?"
        },
        {
          "id": 598977,
          "postDate": "2019-08-14T10:11:00.870Z",
          "content": "<p>Not sure, but I think they may be using \"<em>International clinical diabetic retinopathy disease severity scale</em>\", because it's metioned in <a href=\"https://www.kaggle.com/c/aptos2019-blindness-detection/discussion/103854#latest-597549\">this pdf</a></p>",
          "rawMarkdown": "Not sure, but I think they may be using \"*International clinical diabetic retinopathy disease severity scale*\", because it's metioned in [this pdf](https://www.kaggle.com/c/aptos2019-blindness-detection/discussion/103854#latest-597549)"
        }
      ]
    },
    {
      "id": 599437,
      "postDate": "2019-08-15T00:50:26.803Z",
      "rawMarkdown": "",
      "isDeleted": true
    }
  ],
  "comments": [
    {
      "id": 598135,
      "author_name": "Ashwani Pandey",
      "author_url": "",
      "post_date": "2019-08-13T07:25:39.667000",
      "content": "<p>There are various grading protocols for diabetic retinopathy. For example: <a href=\"http://www.adcis.net/en/third-party/messidor/\">Messidor dataset</a> is graded using following:</p>\n\n<blockquote>\n  <p>0 -&gt; (Normal): (μA = 0) AND (H = 0)\n  1 -&gt; (0 &lt; μA &lt; = 5) AND (H = 0)<br>\n  2 -&gt; ((5 &lt; μA &lt; 15) OR (0 &lt; H &lt; 5)) AND (NV = 0)<br>\n  3 -&gt;(μA &gt;= 15) OR (H &gt;=5) OR (NV = 1)\n  where:\n      μA: number of microaneurysms\n      H: number of hemorrhages\n      NV = 1: neovascularization\n      NV = 0: no neovascularization</p>\n</blockquote>\n\n<p>There are others like Scottish grading protocol.\nDepending on above, category 2 will have symptoms of category 1. For example: If patient has 7 μA and 1 H (category 2), he still has minimum required for category 1.\nSo I guess early signs do not disappear, but is enhanced in a way.</p>\n\n<p><strong>Note:</strong> This is my own understanding. I'll really appreciate if someone with domain knowledge can shed more light.</p>",
      "votes": 2,
      "replies": [
        {
          "id": 598911,
          "author_name": "Rishabh Agrahari",
          "author_url": "",
          "post_date": "2019-08-14T08:04:01.130000",
          "content": "<p>Do you know how current competition's dataset is graded? or how is its grading different than Messidor's?</p>",
          "votes": 0,
          "replies": []
        },
        {
          "id": 598977,
          "author_name": "Ashwani Pandey",
          "author_url": "",
          "post_date": "2019-08-14T10:11:00.870000",
          "content": "<p>Not sure, but I think they may be using \"<em>International clinical diabetic retinopathy disease severity scale</em>\", because it's metioned in <a href=\"https://www.kaggle.com/c/aptos2019-blindness-detection/discussion/103854#latest-597549\">this pdf</a></p>",
          "votes": 0,
          "replies": []
        }
      ]
    },
    {
      "id": 599437,
      "author_name": "",
      "author_url": "",
      "post_date": "2019-08-15T00:50:26.803000",
      "content": "",
      "votes": 0,
      "replies": []
    }
  ],
  "raw_markdown_by_id": {
    "596500": "Dear all,\n\nI was wondering, from a medical perspective, if someone is classified in category 3, they will still show the symptoms of category 1 and 2 on the retina image? Or do the early signs disappear/get replaced by the new symptoms that would put someone if disease category 3?\n\nThank you!",
    "598135": "There are various grading protocols for diabetic retinopathy. For example: [Messidor dataset](http://www.adcis.net/en/third-party/messidor/) is graded using following:\n&gt; \n0 -&gt; (Normal): (μA = 0) AND (H = 0)\n1 -&gt; (0 &lt; μA &lt; = 5) AND (H = 0)<br>\n2 -&gt; ((5 &lt; μA &lt; 15) OR (0 &lt; H &lt; 5)) AND (NV = 0)<br>\n3 -&gt;(μA &gt;= 15) OR (H &gt;=5) OR (NV = 1)\nwhere:\n    μA: number of microaneurysms\n    H: number of hemorrhages\n    NV = 1: neovascularization\n    NV = 0: no neovascularization\n\nThere are others like Scottish grading protocol.\nDepending on above, category 2 will have symptoms of category 1. For example: If patient has 7 μA and 1 H (category 2), he still has minimum required for category 1.\nSo I guess early signs do not disappear, but is enhanced in a way.\n\n**Note:** This is my own understanding. I'll really appreciate if someone with domain knowledge can shed more light.",
    "599437": ""
  }
}